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arthritis, meal, bobby plump , selenium, cholesterol, sugar, unsaturation, essential fatty acids in human, acetic acid, food allergies, saturated and unsaturated fatty acids , | The goal of this study was to elucidate the essential fatty acids. effects of dietary omega-3 fatty acid supplementation on the oxidant/antioxidant status of erythrocytes in rats. The malondialdehyde (MDA) and nitric oxide (NO) levels and the catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GSH-PX) activities were assayed in erythrocytes of male Wistar albino rats after essential fatty acids. 30 days of dietary supplementation with fish oil (0.4 g/kg/day). Erythrocyte CAT activity in the treated group was increased in comparison with essential fatty acids. the control group. Erythrocyte MDA and NO levels were lower in the treated group than the controls. Erythrocyte GSH-Px and SOD activities did not differ significantly in the 2 groups. Negative correlations were found between SOD and CAT activities, and between SOD and GSH-Px activities in the treated group. In conclusion, omega-3 fatty acid supplementation helps to prevent lipid peroxidation and to safeguard erythrocytes from oxidative injury. |
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Articles by Fadillioglu, E. Articles citing this Article PubMed PubMed Citation selenium Articles by Iraz, M. Articles by selenium Fadillioglu, E. Annals of Clinical & Laboratory Science 35:169-173 (2005) © 2005 Association of Clinical selenium Scientists Brief Communication Omega-3 Essential Fatty Acid Supplementation and Erythrocyte Oxidant/Antioxidant Status in Rats Mustafa Iraz1, Hasan Erdogan2, Birsen Ozyurt3, Fikret Ozugurlu4, Salih Ozgocmen5 and Ersin Fadillioglu6 1 Departments of Pharmacology and 6 Physiology, Inonu University Faculty of Medicine, Malatya; 2 Departments of Physiology, 3 Anatomy, and 4 Biochemistry, Gaziosmanpasa University Faculty of Medicine, Tokat; and 5 Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Firat University Faculty of Medicine, Elazig,Turkey Abstract Fish oil contains large amounts of essential omega-3 fatty acids, such as eicosapentaenoic and docosahexaneoic acids, which are building structures of cell membranes. |
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