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At the end of each cycle of four reactions, one acetyl-CoA two-carbon unit is released from the end of the fatty acid, which then goes through another round of beta-oxidation, continuing to oxidize and shorten even-chain fatty acids until they are entirely converted to acetyl-CoA. Fatty acids with an odd number of carbons in the acyl chain are left at the fat black girls end with fat black girls propionyl-CoA, with 3 carbons, which fat black girls cannot enter another round of beta-oxidation. The propionyl-CoA produced in this manner is converted to succinyl-CoA that then enters the Krebs cycle (see pathway).The acetyl-CoA generated in beta-oxidation enters the Krebs cycle, where it is further oxidized to CO2, producing more reduced energy carriers, NADH and FADH2 (See Krebs cycle pathway). These carriers produced in the Krebs cycle, along with those produced directly in beta-oxidation, transfer their energy to the electron transport chain where they drive the creation of the proton gradient that supports mitochondrial ATP production.
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