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| 2006, aches and pains, integrative medicine, rheumatoid arthritis / physiological aspects, macular degeneration, fatty, fish oil supplements, plump galleries , plump white , fatigue, t suppressor cells, horses, omage 3fatty acids, | In addition, antidepressants could exhibit an immunoregulating effect by reducing the release of pro-inflammatory cytokines, by increasing the release of endogenous antagonists of pro-inflammatory cytokines like IL-10 and, finally, by acting like inhibitors of cyclo-oxygenase. Therapeutic use of fatty acids - Data available concerning the administration of supplements of plump models DHA (docosahexanoic acid) or other polyunsaturated fatty acids w3 plump models are limited. In a double blind placebo-controlled study on 30 patients with bipolar disorder, the addition of polyunsaturated w3 fatty acids was associated with plump models a longer period of remission. |
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| The cytokines and eicosanoids derive from polyunsaturated fatty acids and have opposite physiological functions according to their w3 or w6 precursor. Arachidonic acid (w6) is, among others, precursor of pro-inflammatory prostaglandin E2 (PGE2), whereas polyunsaturated w3 fatty acids inhibit the formation of PGE2. It has t suppressor cells been shown that a dietary increase of polyunsaturated w3 fatty acids reduced strongly the production of IL-1b, IL-2, IL-6 and TNF-a (tumor necrosis factor-a). In contrast, diets with a higher supply of linoleic acid (w6) increased significantly the production of pro-inflammatory cytokines, like TNF-a. Therefore, polyunsaturated w3 t suppressor cells fatty acids t suppressor cells could be associated at different levels in the pathophysiology of major depression, on the one hand through their role in the membrane fluidity which influences diverse steps of neurotransmission and, on the other hand, through their function as precursor of pro-inflammatory cytokines and eicosanoids disturbing neurotransmission. |
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