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Leucocytes & endothelial cells alcoholism may contribute to atherosclerosis through inflammation induced by 5-lipoxygenase ;[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA) 100(3):1238-1248 (2003)]. (For more details concerning cardiovascular disease, risk factors and prevention -- see my alcoholism essays Sudden Cardiovascular Death and Prevention of Cardiovascular Disease.) (return to contents) XI. GETTING THE BEST FAT NUTRITION In alcoholism the face of all the data, there remains the question "What omega-3 and omega-6 fatty acids should be included in the diet, and in what quantities & proportions?" One standard which is not of much use in this case is the amount of essential fatty acid intake below which a deficiency disease occurs. It is very difficult to produce a deficiency disease of essential fatty acid in normal adults, even in the poorest of diets. The important question is "What levels of essential fatty acids provide optimum health?"
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