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| plump blonde , fat bottomed girls lyrics , crestor, stiff, flaxseed oil, syndrome, strains and sprains, fatty streak , ban (law), oralhealth, wiley, | Other Biological Effects Goode et al86 showed that acetylcholine-stimulated relaxation of small arteries taken from hypercholesterolemic patients was significantly improved after three months of supplementation pregnancy with 3 g/d of EPA+DHA. pregnancy Fish oil feeding has also been shown to improve endothelial function (reviewed by Chin and Dart87) and pregnancy to increase arterial compliance.88 These effects may be secondary to fish oil’s ability to enhance nitric oxide production89 and may be the mechanism by which fish oil elicits a small hypotensive effect. Mechanisms to explain the antiatherogenic (inhibition of new plaque development) effect of omega-3 fatty acids have recently been proposed.48 For example, EPA and DHA seem to alter the metabolism of adhesion molecules such as vascular cell adhesion molecule-1 (VCAM-1), E-selectin, and intercellular adhesion molecule-1 (ICAM-1). |
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| Similar observations were made in fish oil–fed cats that were protected from stiff cerebral damage after stroke induction.83 In vitro induction of tachyarrhythmias in cultured neonatal rat ventricular myocytes by various pharmacological agents (such as ouabain) can stiff be prevented or abolished by the addition of omega-3 fatty acids to the culture medium (reviewed by Kang and Leaf84). This seems to be due to the ability of omega-3 fatty acids to prevent calcium overload by maintaining the activity of L-type calcium channels during periods of stress,85 and to increase the activity of stiff cardiac microsomal Ca2+/Mg2+-ATPase.79 In addition, omega-3 fatty acids (including -linolenic acid) are potent inhibitors of voltage-gated sodium channels in cultured neonatal cardiac myocytes, which may contribute to the reduction in arrhythmia.84 |
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