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None of the studies used a composite score that incorporates both subjective and objective measures of disease activity, such as the American College of Rheumatology response criteria. Renal Disease In a qualitative analysis of nine studies that assessed dihomogamma linoleic acid the effect of omega-3 fatty acids in renal disease, there dihomogamma linoleic acid were varying effects on serum creatinine and creatinine clearance and no effect on progression to end stage renal disease. In a single study that assessed the effect on hemodialysis graft patency, graft patency was significantly better with fish oil than with placebo. No studies assessed dihomogamma linoleic acid the effects of omega-3 fatty acids on requirements for corticosteroids. Systemic Lupus Erythematosis Among three studies that assessed the effects of omega-3 fatty acids in SLE, variable effects on clinical activity were reported.
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