Measuring fatty acid levels fatty infiltration of liver membrane

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Measuring fatty acid levels in the blood cell membranes (plasma phospholipids) in children with autism, one preliminary study found that membrane average, total levels of omega-3 membrane (n-3 PUFAs) in the autistic children were about 20% lower than in mentally retarded children used as controls.1 Levels of one important n-3 fat, docosahexaenoic acid (DHA), were 23% lower. These deficiencies resulted in a significantly higher ratio of n-6 to n-3 PUFAs in the autistic children. "These results open up membrane very interesting perspectives for the investigation of a new biological index in autism," the researchers wrote. Abnormalities of fatty acid and membrane phospholipid metabolism may play a part in a wide range of neurodevelopmental and psychiatric disorders.
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