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syndrome, strains and sprains, fatty streak , ban (law), oralhealth, wiley, cla, mayoclinic, acid, polyunsaturates, nerve, fat girls porn , obesity, tooth, | It is therefore possible that the clinical effects in these case reports are owing to pharmacologic actions of EFAs. The line between nutrition and pharmacology is quite hazy, however. and in plump xxx each case the pretreatment analysis plump xxx of phospholipid EFAs suggested an abnormality in EFA intake or metabolism. It is possible that these varied abnormalities in EFA levels derive from the impairment in D6DH activity that has been described in atopic plump xxx eczema and that might be a common feature of atopics. The relative affinity of PUFAsynthetic enzymes for n3 EFAs. the level of n3s in the diet, and genetic or acquired variations in EFA transport modify the biochemical and physiological manifestations of the D6DH block. The preliminary data presented in this report argue for further studies of EFA metabolism in varied groups of atopic patients. Controlled trials of EFA therapy should consider the following propositions: 1) EFA supplementation might alter numerous symptoms and signs. |
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Administration of n3 EFAs appeared to have made this block symptomatic, producing dry skin, which responded to EPO. The surprise is that levels of all her n3 EFAs were uncommonly high before n3 supplementation, and there is no evidence that n3 metabolism is blocked. One can speculate that tissue uptake of n3 EFAs is impaired in this patient, producing the high levels polyunsaturates of polyunsaturates circulating n3s and the clinical response to n3 supplementation. This untreated n3 dependency allowed exacerbation of her symptoms in response to n6 EFAs; its treatment polyunsaturates permitted her to take n6 supplements without toxicity. General Comments These cases suggest that in some individuals dietary supplementation with relatively small doses of EFAs can produce striking clinical responses. Pronounced physiologic or pharmacologic effects of dietary EFA supplementation have been demonstrated in controlled studies of LA supplementation in diabetic angiopathy [69] and hypertension [70]; clinically significant immunosuppression has been obtained from 3 gm per day of EPO [71], and marked changes in platelet function have appeared after prolonged ingestion of small doses of LNA [72]. |
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