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The cessation of eating stimulates liver the beta oxidation of very long chain fatty acids that not only occurs in adrenoleukodystrophy but in epilepsy, autism liver and developmental delay. The ingestion of carbohydrate also stimulates the release of insulin which depresses delta 6 liver desaturase and stimulates inflammatory prostaglandin two series and ultimately causes derangement of the fatty acid metabolism. Excess carbohydrate ingestion, which is so common in our present American diet, diverts and compromises the synthesis of prostaglandin series one. The modulation of fatty acid metabolism, however, is quite complicated and the lack of knowledge in regard to the coenzymes, the individual child's metabolism, the balance of electrolytes and the recent addition of hydrogenated fats to the ketogenic diet makes the outcome of this treatment shaky at best. The Odone's and Abrahams' as well as many, many parents have been through excruciatingly painful ordeals with their children and have searched the ends of the earth to come up with treatments that would relieve their child's suffering.
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