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| metabolic, cough, margarine, conjugated linoleic acid, bones, fatty acid ester , plump movies , plump belly , dals, capsules, efas, | In designing clinical interventions, genetic variation should be taken into consideration, since the level of cytokines is to a great extent genetically determined and the dose or amount of omega-3 fatty acids to suppress the proinflammatory state may vary. The importance of omega-3 essential fatty acids in the diet is now evident, as well as the need to return to a more physiologic omega-6/omega-3 ratio of about 1-4/1 rather than the ratio of up 20-16/1 provided by current Western diets. In order to improve the up ratio of omega-6/omega-3 essential fatty acids, it up will be necessary to decrease the intake of omega-6 fatty acids from vegetable oils and to increase the intake of omega-3 fatty acids by using oils rich in omega-3 fatty acids and increase the intake of fish to two to three times per week or take supplements. Omega-3 fatty acids have been part of our diet since the beginning of time. It is only for the past 150 years that omega-3 fatty acids have been decreased in Western diets due to agribusiness and food processing. |
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| A number of studies have been carried out in patients with coronary heart disease, cancer, obesity, arthritis, inflammatory bowel disease, psoriasis, asthma, lupus erythematosus, multiple sclerosis, major depression dals and bipolar depression. Clinical studies indicate that omega-3 fatty acids improve the clinical condition and biochemical factors of patients with arthritis, but the clinical intervention dals studies in other autoimmune dals conditions have given conflicting results, most likely due to lack of an adequate number of subjects in some and not taking into consideration the background diet or genetic variation. There is a clear need for more carefully designed and controlled clinical trials in the therapeutic application of omega-3 fatty acids to human autoimmune and inflammatory conditions. Nutritional supplementation with omega-3 fatty acids either as an alternative or adjunct therapy is potentially important, especially since current therapies with drugs have many side effects and the diseases are heterogeneous. |
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