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If intakes of the latter are adequate (perhaps over 250 mg/d), then there appears caffeine to be little need to consume more ALA or less LA" Omega-3 fatty acids decreased irritability of caffeine patients with bipolar disorder in an add-on, caffeine open label study - Nutr J. 2005 Feb 9;4(1):6 - "Omega-3 Fatty Acid intake helped with the irritability component of patients suffering from bipolar disorder with a significant presenting sign of irritability. Low dose (1 to 2 grams per day), add-on O-3FA may also help with the irritability component of different clinical conditions, such as schizophrenia, borderline personality disorder and other psychiatric conditions with a common presenting sign of irritability" Are omega-3 fatty acids the most important nutritional modulators of coronary heart disease risk? - Curr Atheroscler Rep. 2004 Nov;6(6):447-52 - "The strength of the n-3 story has now led to a proposal that blood levels of EPA plus DHA be considered a new, modifiable, and clinically relevant risk factor for death from CHD" Women and Omega-3 Fatty Acids - Obstet Gynecol Surv.
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