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These effects appear to be due to the correction of an underlying EFA deficiency, since these patients' prostatic and seminal lipid levels and ratios are often abnormal. Gamma-linolenic acid (GLA), which is derived from evening primrose oil and young fat girls borage oil, appears to be a powerful 5-alpha reductase inhibitor.  Chronic Renal Insufficiency There have been a variety of trials of omega-3 fatty acid supplementation in patients with a young fat girls variety of renal disorders. These trials suggest that such therapy may be of use in the treatment of IgA nephropathy young fat girls and chronic renal failure. Dietary polyunsaturated fatty acid manipulation results in an anti-inflammatory. [Polyunsaturated Fatty Acids and Renal Disease, Proceedings of the Society For Experimental Biology and Medicine, 1996;213: pp.13-23.]Fish oil supplementation is promising and does not produce the risks associated with corticosteroid and immunosuppressive drug use.Respiratory  COPD
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