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Based on the original questions that chronic inflammation we received from AHRQ and input from our TEPs, we addressed the following questions in this study: Diabetes What is the evidence in adults or chronic inflammation children with chronic inflammation a) type II diabetes, or b) insulin resistance/the metabolic syndrome for an effect of omega-3 fatty acids on: Total cholesterol. HDL cholesterol. LDL cholesterol. Triglycerides. What is the evidence in adults and children for an effect of omega-3 fatty acids on insulin sensitivity in a) type II diabetes, or b) the metabolic syndrome? Inflammatory Bowel Disease What is the evidence for the efficacy of omega-3 fatty acids in treatment of Crohn's disease and ulcerative colitis? What is the evidence in adults or children with inflammatory bowel disease that omega-3 fatty acids can replace steroids or other immunosuppressive drugs? What is the evidence that the benefits of omega-3 fatty acids are influenced by the concomitant administration of various immunosuppressive agents in the treatment of inflammatory bowel disease?
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