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disturbances, endometriosis, plump wife , fatty acids definition , 6, hplc, atkins, miss plump , complete, female, macrobiotic, plump pussies , phytoestrogen, proteomics, prevention, excercise, lipids, glycerol and fatty acids , mental illness, | These situations are handled by an additional rheumatoid two enzymes: cis-δ3-Enoyl CoA isomerase and 2,4 Dienoyl CoA reductase. Whatever the conformation of the hydrocarbon chain, β-oxidation occurs normally until the acyl CoA (because of the presence of a double bond) is not an appropriate substrate for acyl CoA dehydrogenase, or enoyl CoA hydratase. If the acyl CoA contains a cis-Δ3 bond, then the isomerase will rheumatoid convert the bond to a trans-Δ2 bond, which is a regular substrate. If the acyl CoA contains a cis-Δ4 double bond, then its dehydrogenation yields a 2,4-dienoyl intermediate, which is not a substrate for rheumatoid enoyl CoA hydratase. However, the enzyme 2,4-Dienoyl CoA reductase reduces the intermediate, using NADPH, into trans-Δ3-enoyl CoA. |
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The end product is L-3-hydroxyacyl CoA. [edit] Oxidation by NAD+ The third step is the oxidation of L-3-hydroxyacyl CoA by NAD+, catalyzed by L-3-hydroxyacyl CoA dehydrogenase. This converts the hydroxyl group into a keto group. The end product is 3-ketoacyl CoA. [edit] Thiolysis The final step is the cleavage of 3-ketoacyl CoA by the thiol group of another molecule of disturbances CoA. This reaction disturbances is catalyzed by Β-ketothiolase. The thiol is inserted between C-2 and C-3, which yields an acetyl disturbances CoA molecule and an acyl CoA molecule, which is two carbons shorter. This process continues until the entire chain is cleaved into acetyl CoA units. For every cycle, one molecule of FADH2, NADH and acetyl CoA are formed. [edit] β-oxidation of unsaturated fatty acids β-oxidation of unsaturated fatty acids poses a problem since the location of a cis bond can prevent the formation of a trans-δ2 bond. |
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