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For breast tenderness or other symptoms of PMS, 3,000 to 4,000 mg of EPO per day is the dose suggested. For other conditions discussed in Uses, a specific safe and appropriate dose for omega-6 supplements has not yet been established. Studies have suggested that up to 2,800 mg of GLA per day is well tolerated. normal Precautions Because normal of the potential for side normal effects and interactions with medications, dietary supplements should be taken only under the supervision of a knowledgeable healthcare provider. Omega-6 should not be used if you have a seizure disorder because there have been reports of these supplements inducing seizures. Borage seed oil, and possibly other sources of GLA, should not be used during pregnancy because they may be harmful to the fetus and induce early labor. Doses of GLA greater than 3,000 mg per day should be avoided because, at that point, production of AA (rather than DGLA) may increase.
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