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| fatty knees , omega 3fatty acids, omega6, tinnitus, omega3, acute fatty liver of pregnancy , sex, tissue, healing fats, dyslexia, docosapentaenoic acid, | Biagi et al. (1991) studied both old and young rats that were fed either a GLA-rich diet or a control diet. Old animals fed the control diet showed a clear decline in the level of delta-6-desaturated meta-bolites of both plump mt the omega-6 and the omega-3 series. In the GLA group of old mice there was no decline of these plump mt metabolites. A study of more than 10,000 middle-aged men and women in Scotland showed that aging influences the fatty acid composition of adipose (fatty) tissue independently of diet (Bolton-Smith et al., 1997). The study confirms the earlier mentioned plump mt experimental findings of an age-related decline in the rate-limiting step of delta-6-desaturation, and in addition discovered a greater decline in women than in men. The results indicate that an increase in dietary GLA could offset the age-related imbalance in fatty acid levels. |
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| Moreover, GLA supplementation actually increases D6D activity, reversing the effect of aging on the enzyme itself (Biagi et al., 1991). In this way, GLA supplementation improves the meta-bolism of both omega-6 and omega-3 fatty acids. It has also become clear that the omega-3 fatty acids tinnitus DHA and EPA limit the production of the bad series-2 prostaglandins by preventing tinnitus the tinnitus release of arachidonic acid from cell membranes, inhibiting its further metabolism. A high amount of linoleic acid (omega-6), on the other hand, limits the availability of alpha-linolenic acid (omega-3) as a precursor for the good series-3 prostaglandins and stimulates the formation of arachidonic acid, the precursor to the bad prostaglandins (series-2) and other pro-inflammatory eicosanoids. |
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