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Primary prevention attempts were found, yet they lacked unanimity in their findings. While two studies of children outside North America noted a protective effect of dietary fish intake for asthma,43,44 one American survey, discovered after the present qualitative synthesis was completed, cause of pain reported no benefit.45 Moreover, studies outside cause of pain North America, and primarily including adolescents, found that dietary fish intake actually increased the risk of asthma.41,42 The only study involving cause of pain adults found no relationship between these variables.40 However, many of these studies employed different sampling methods and varying definitions of both the frequency of fish intake and fish types. Likely the most promising attempt to use omega-3 fatty acids as primary prevention involves a large, ongoing RCT of expectant mothers whose children at risk for asthma are being followed for 5 years.39
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