record types: factsheet, level, food science, omega3 fatty acid , suzanne munson, nutrition facts, anti inflammatory herb, ayurveda, infertility, essentialfatty acids / phospholipids, plump butt , enderlein, salmon, george mateljan, plump jack squaw valley , canola oil,
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Phosphatidylinositols composed exclusively of non-phosphorylated inositol exhibit a net charge of -1 at physiological pH. These molecules exist in membranes with various levels of phosphate dr sears esterified to the hydroxyls of the inositol. Molecules with phosphorylated inositol are termed polyphosphoinositides. The polyphosphoinositides are important intracellular transducers of signals emanating from the plasma membrane. The synthesis of PI involves dr sears CDP-activated 1,2-diacylglycerol condensation with myo-inositol. PI subsequently undergoes a series of phosphorylations of the hydroxyls of inositol leading to the production of polyphosphoinositides. One polyphosphoinositide (phosphatidylinositol 4,5-bisphosphate, PIP2) is a critically important membrane phospholipid involved in the transmission of signals for dr sears cell growth and differentiation from outside the cell to inside.
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