Within the protein are health/fitness essentialfatty acids / phospholipids
record types: factsheet, level, food science, omega3 fatty acid , suzanne munson, nutrition facts, anti inflammatory herb, ayurveda, infertility, essentialfatty acids / phospholipids, plump butt , enderlein, salmon, george mateljan, plump jack squaw valley , canola oil, They also play important roles in inhibiting gastric acid secretion, regulating blood pressure through vasodilation or constriction, and inhibiting or activating platelet aggregation and thrombosis. The principal eicosanoids of biological significance to humans are a group of molecules derived from the C20 fatty acid, arachidonic acid. Minor eicosanoids are derived from eicosopentaenoic acid which is itself derived from a-linolenic acid obtained in the diet. The major source of arachidonic acid is through its release from cellular stores. Within the cell, it resides health/fitness predominantly at the C-2 position of membrane phospholipids health/fitness and is released from there upon the activation of health/fitness phospholipase A2 (see diagram above).
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Within the protein are regions of homology to the transmembrane domain of the morphogen receptor patched (of Drosophila melanogaster), the sterol-sensing domain (SSD) of SREBP essentialfatty acids / phospholipids (sterol regulated element binding protein) cleavage-activating essentialfatty acids / phospholipids protein, SCAP and essentialfatty acids / phospholipids HMG-CoA reductase. back to the top Metabolism of the Eicosanoids The eicosanoids consist of the prostaglandins (PGs), thromboxanes (TXs) and leukotrienes (LTs). The PGs and TXs are collectively identified as prostanoids. Prostaglandins were originally shown to be synthesized in the prostate gland, thromboxanes from platelets (thrombocytes) and leukotrienes from leukocytes, hence the derivation of their names. Structures of Representive Clinically Relevant Eicosanoids PGE2 TXA2 LTA4 The eicosanoids produce a wide range of biological effects on inflammatory responses (predominantly those of the joints, skin and eyes), on the intensity and duration of pain and fever, and on reproductive function (including the induction of labor).
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