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What is the efficacy or association of omega-3 fatty acids in preventing incident CVD events in people without known CVD (primary prevention) and with known CVD (secondary prevention)? How does the efficacy or plump fiction association of omega-3 fatty acids in preventing incident CVD events differ in subpopulations, including men, pre-menopausal plump fiction women, post-menopausal women, and different age groups? What are the effects of potential confounders—such plump fiction as lipid levels, body mass index, blood pressure, diabetes, aspirin use, hormone replacement therapy, and cardiovascular drugs—on associations found in prospective cohort studies? What is the relative efficacy of omega-3 fatty acids on different CVD outcomes? Can the CVD outcomes be ordered by strength of treatment effect of omega-3 fatty acids?
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