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Excessive thirst is common. it has been noted in EFA-deficient animals 1641 and in a dr sears population of allergic hyperactive children [65]. The mechanism of excessive thirst in experimental EFA deficiency is thought to be an increase in transdermal water loss owing to defective barrier function of the skin. It responds rapidly to treatment with LA or GLA dr sears but not with DGLA or AA [64]. How LA or GLA enhance dermal barrier function is uncertain. dr sears Although this child was treated with several interventions, all his symptoms returned and remitted with changes in his use of EPO. An excessive dose of EPO appeared to cause adverse side effects, in this case irritability and anorexia. Reversible toxic reactions to EPO overdosage are not unusual in allergic children; they confirm the physiologic potency of dietary GLA. Case 2 This 26-year-old woman, with chronic fatigue and nasal congestion, presented for evaluation of dysmenorrhea of 7 years' duration.
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