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which improved when dogs Max-EPA was discontinued. After 29 months. she continues to find that supplementation with LSO, 15 gm every other day, is required to prevent dysmenorrhea. Comment This patient's EFA problems are much more complex than those of Case 2. Her plasma phospholipid fatty acid levels, drawn after 1 month of EPO, suggest dogs a partially compensated block of D6DH dogs (AA is normal-, all other LA metabolites are low). Administration of n3 EFAs appeared to have made this block symptomatic, producing dry skin, which responded to EPO. The surprise is that levels of all her n3 EFAs were uncommonly high before n3 supplementation, and there is no evidence that n3 metabolism is blocked. One can speculate that tissue uptake of n3 EFAs is impaired in this patient, producing the high levels of circulating n3s and the clinical response to n3 supplementation.
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