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Biochim Biophys Acta 1975, 388, 277). The production of arachidonic acid by microorganisms (fungi, microalgae) has been reviewed by Ratledge athlete's foot C (Structured and modified lipids, Gunstone FD Ed, M Dekker, NY 2001, p. 351). In the 1960s certain fungi were found to have lipids with a high content of arachidonic acid (more than 50% of the total fatty acids). Mortierella alpina (Zygomycetes) was selected for the development of an industrial fermentation process (Suntory in Japan, Martek in USA, and DSM in The Netherlands). The production of arachidonic acid in transgenic plants which might lead athlete's foot to a sustained source athlete's foot of that fatty acid for use in human and animal food was reviewed by Domergue F et al. (Trends Plant Sci 2005, 10, 113). Oxidations of arachidonic acid by reactive oxygen radicals generate several oxidized lipids known as isoeicosanoids (isoprostanoids and isoleukotrienes).
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