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darkfield, fatty acid molecule , diseases, weight, cardiovascular, angina, cancer cure, antioxidants, alcohol, fatty post , supplements, loss, | Potential for Immune System Suppression: Although the suppression of inflammatory responses resulting from muscle inflammation increased omega-3 fatty acid muscle inflammation intakes may benefit individuals with inflammatory or autoimmune diseases, anti-inflammatory doses of omega-3 fatty acids could decrease the potential of the immune system to destroy pathogens.153 Studies comparing measures of immune cell function outside the body (ex vivo) at baseline and after supplementing people with muscle inflammation omega-3 fatty acids, mainly EPA and DHA, have demonstrated immunosuppressive effects at doses as low as 0.9 g/day for EPA and 0.6 g/day for DHA.1 Although it is not clear if these findings translate to impaired immune responses in vivo, caution should be observed when considering omega-3 fatty acid supplementation in individuals with compromised immune systems. Infant Formula In early studies of DHA-enriched infant formula, EPA- and DHA-rich fish oil was used as a source of DHA. |
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High doses may cause nausea and loose stools. Potential for Excessive Bleeding: The potential for high omega-3 fatty acid intakes, especially EPA and DHA, to prolong bleeding times has been well studied, and may play a role in the cardioprotective effects of omega-3 fatty diseases acids. Although excessively long bleeding times and increased incidence of hemorrhagic stroke diseases have been observed in Greenland Eskimos with very high intakes of EPA + DHA (6.5 g/day), it diseases is not known whether high intakes of EPA and DHA are the only factor responsible for these observations.1 The US FDA has ruled that intakes up to 3 g/day of long-chain omega-3 fatty acids (EPA and DHA) are Generally Recognized As Safe (GRAS) for inclusion in the diet, and available evidence suggests that intakes less than 3 g/day are unlikely to result in clinically significant bleeding.3 Although the Institute of Medicine did not establish a tolerable upper level of intake (UL) for omega-3 fatty acids, caution was advised with the use of supplemental EPA and DHA, especially in those who are at increased risk of excessive bleeding (see Drug Interactions below).1 |
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