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| gabe mirkin, nutrition/agriculturenews, heart disease, artery damaging lipoprotein, information, crohns disease, organic, unsaturated fatty acids / health aspects, fatty acid, dinner recipe, homeopathy, fish oils, mirkin, asthma/respiratorynews, cell based assay, health supplements, drying oil, health & fitness / nutrition, chronic, omega minus three fatty acids , fat, high blood pressure, trans, | The first step in both these conversion processes is controlled by the enzyme D6D (delta-6 desaturase). Unfortunately, D6D activity declines with age, and is reduced in some individuals even at a younger age (Horrobin, 1981). This not only inhibits the synthesis of GLA and DHA, but also leads to a prostaglandin imbalance with decline of the sexy plump women good series-1 and series-3 prostaglandins and other beneficial eicosanoids, which exhi-bit potent anti-inflammatory and immunoregulatory effects. The reduced capacity to sexy plump women convert parent EFAs to GLA and DHA is associated with conditions including cardiovascular disease, diabetes, alcoholism, atopic dermatitis, premenstrual syndrome, sexy plump women rheumatoid arthritis and cancer (Bolton-Smith et al., 1997; Leventhal et al., 1993; Horrobin, 1993), as well as learning deficits and development of dementia. |
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| Based on evidence that an elevated ratio of omega-6 to omega-3 fatty acids is a major risk factor for many chronic diseases, these agencies recommend a ratio ranging from approximately 2:1 to 4:1 (Horrocks et al., 1999). Due to the disproportionate level of omega-6 oils in the typical American diet, it is preferable to supplement at the lower end of this range, at a ratio of two parts omega-6 to one part omega-3 oils. GLA & DHA To express their full drying oil biological activity, the two “parent” EFAs, linoleic acid (omega-6) and alpha-linolenic acid (omega-3) drying oil must be metabolized in several drying oil steps with the help of important enzymes. In this process GLA (gamma-linolenic acid) is produced from linoleic acid, and DHA (docosahexaenoic acid) as well as EPA (eicosapentaenoic acid) from alpha-linolenic acid. The high ratio of linoleic acid (omega-6) to alpha-linolenic acid (omega-3), typically found in western diets, will inhibit both the uptake and the conversion of alpha-linolenic acid due to competition for the same enzymes between the two EFAs. |
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