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gabe mirkin, nutrition/agriculturenews, heart disease, artery damaging lipoprotein, information, crohns disease, organic, unsaturated fatty acids / health aspects, fatty acid, dinner recipe, homeopathy, fish oils, mirkin, asthma/respiratorynews, cell based assay, health supplements, drying oil, health & fitness / nutrition, chronic, omega minus three fatty acids , fat, high blood pressure, trans, | Biagi et al. (1991) studied both old and plump women young rats that were fed either a GLA-rich diet or a control diet. Old animals fed the control diet showed a clear decline in the level of delta-6-desaturated meta-bolites of both the omega-6 and the omega-3 series. In the GLA group of old plump women mice there was no decline of these metabolites. A study of more than 10,000 middle-aged men and women in Scotland plump women showed that aging influences the fatty acid composition of adipose (fatty) tissue independently of diet (Bolton-Smith et al., 1997). The study confirms the earlier mentioned experimental findings of an age-related decline in the rate-limiting step of delta-6-desaturation, and in addition discovered a greater decline in women than in men. |
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The exciting news is that supplementation with GLA and DHA can circumvent impaired D6D function, and restore levels of the good prostaglandins. Moreover, GLA health & fitness / nutrition supplementation actually increases D6D activity, reversing the effect of aging on the enzyme itself (Biagi et al., 1991). In this way, GLA supplementation improves the meta-bolism of both omega-6 and omega-3 fatty acids. It has also become clear that the omega-3 fatty acids DHA and EPA limit the production of the bad series-2 prostaglandins by preventing the release of arachidonic acid from cell membranes, inhibiting its health & fitness / nutrition further metabolism. A high amount of linoleic health & fitness / nutrition acid (omega-6), on the other hand, limits the availability of alpha-linolenic acid (omega-3) as a precursor for the good series-3 prostaglandins and stimulates the formation of arachidonic acid, the precursor to the bad prostaglandins (series-2) and other pro-inflammatory eicosanoids. |
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