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Studies that presented platelet fatty acid chain aggregation data in graphical format only were not analyzed. Coronary Artery Restenosis We performed a meta-analysis of the 12 randomized trials that reported restenosis rates after coronary angioplasty. All 12 trials evaluated fish oils. We found heterogeneity of results across studies but an overall trend toward a net reduction of relative risk of 14 percent with fish oil intake. Two studies reported no significant difference in effect in men and women. Five additional non-randomized fatty acid chain studies were not analyzed. Carotid Artery Intima-Media Thickness fatty acid chain The four available studies of carotid IMT were heterogeneous. The randomized trial found no effect of fish oil, but two cross-sectional studies found that dietary omega-3 fatty acid was correlated with thinner IMT. The cohort study of plant oil margarine was inconclusive. Exercise Tolerance Testing The six available studies of exercise tolerance testing suggest that fish oil consumption may benefit exercise capacity among patients with coronary artery disease, although the effect may be small.
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