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Among the 60 studies analyzed for other outcomes that reported data on percent phospholipid levels, we analyzed the 30 randomized trials diet / health / fitness with diet / health / fitness data on at least 25 subjects in parallel trials and 20 subjects in crossover trials who consumed omega-3 fatty acids. The correlation between dose and change in level appears to be fairly uniform, where 1 g supplementation of EPA and/or DHA corresponds to approximately a one percent increase in EPA+DHA level. Granulocyte and monocyte membrane phospholipid levels also increased after omega-3 fatty acid supplementation in individual studies. Return to Contents Discussion diet / health / fitness Overall, there is strong evidence that fish oils have a strong beneficial effect on Tg that is dose-dependent and similar in various populations. There is also evidence of a very small beneficial effect of fish oils on blood pressure and possible beneficial effects on coronary artery restenosis after angioplasty, exercise capacity in patients with coronary atherosclerosis, and possibly heart rate variability, particularly in patients with recent myocardial infarctions.
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