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A meta-analysis19 of 31 trials and a total of 1,356 patients plump moms found that 5.6 g per day of fish oil reduced blood pressure plump moms by 3.4/2.0 mm Hg. Similarly, another study20 found modest blood pressure reductions of 5.5/3.5 mm Hg in trials in which patients received at least 3 g per day of fish oil. A meta-analysis21 of 36 trials found that a median dosage of 3.7 g per day of fish oil reduced systolic blood pressure plump moms by only 2.1/1.6 mm Hg. rheumatoid arthritis Several small studies21-24 have found that fish oil at dosages of at least 3 g per day (one study22 used 18 g per day) significantly reduced morning stiffness and the number of tender, swollen joints in patients with rheumatoid arthritis. These beneficial effects were more common in patients receiving higher dosages of fish oil and were not apparent until fish oil had been consumed for at least 12 weeks.22,24 It has been reported that reducing dietary intake of omega-6 fatty acids while increasing consumption of omega-3 fatty acids reduces the inflammatory mediators of rheumatoid arthritis and, consequently, allows some patients to reduce or discontinue use of nonsteroidal anti-inflammatory drugs.24-26
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