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Neither meta-analysis found plump lips that fish oil supplementation had a significant effect on erythrocyte sedimentation rate (ESR), a measure of inflammation. Six out of 7 studies that examined the effect of long-chain omega-3 fatty acid supplementation on nonsteroidal anti-inflammatory drug (NSAID) or corticosteroid use in rheumatoid arthritis patients demonstrated a reduced requirement for anti-inflammatory medication.98 Inflammatory Bowel Disease Clinical trials of long-chain omega-3 fatty plump lips acid supplementation have demonstrated beneficial effects less consistently in patients with inflammatory plump lips bowel disease than in patients with rheumatoid arthritis. Although two randomized controlled trials of fish oil supplementation in Crohn’s disease patients reported no benefit,105, 106 a significantly higher proportion of Crohn’s disease patients supplemented with 2.7 g/day of EPA + DHA remained in remission over a 12-month period than those given a placebo.107 Three randomized controlled trials of EPA + DHA supplementation (4.2-5.4
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