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Recent studies have produced conflicting results with regard to the effects of methylmercury on CHD risk.20,21 Thus, the extent to which methylmercury in fish may mask the beneficial effects of omega-3 fatty acids requires further study. Fish consumption has been shown to be related to reduced splenda sudden cardiac death. In a population-based, nested, case-control study, a strong negative relationship was reported between splenda fish intake and risk for sudden death (ie, 5.5 g of omega-3 fatty acids per splenda month, equivalent to two fatty fish meals per week, was associated with a 50% reduced risk of primary cardiac arrest).22 In the US Physicians’ Health Study, men who consumed fish at least once weekly had a relative risk of sudden death of 0.48 (P=0.04) versus men who consumed fish less than once per month.12 A recent report from the Physicians’ Health Study23 reported an inverse relationship between blood levels of long-chain omega-3 fatty acids and risk of sudden death in men without a history of CVD.
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