This enzyme is activated breast margarin

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This enzyme is activated by citrate and inhibited by palmitoyl-CoA and other long-chain fatty acyl-CoAs. ACC activity margarin can also be affected by margarin phosphorylation. For instance, glucagon-stimulated increases in PKA activity result in the phosphorylation of certain serine residues in ACC leading to decreased activity of the enzyme. By contrast, insulin leads margarin to PKA-independent phosphorylation of ACC at sites distinct from glucagon, which bring about increased ACC activity. Both of these reaction chains are examples of short-term regulation. Insulin, a product of the well-fed state, stimulates ACC and FAS synthesis, whereas starvation leads to a decrease in the synthesis of these enzymes. Adipose tissue levels of lipoprotein lipase also are increased by insulin and decreased by starvation. However, the effects of insulin and starvation on lipoprotein lipase in the heart are just the inverse of those in adipose tissue.
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