|
lipids, glycerol and fatty acids , mental illness, lower your cholesterol, weight loss, plump women galleries , nude fat girls , coconut fatty acid , biotechnology, margarin, back pain, thyroid disease, lupus, plump mature , saturated fats, treatment for fatty liver , burns, bronchitis, ear, symptoms of fatty liver , skin, plump princess , joint pain,
|
The metabolism of fat is regulated by two distinct mechanisms. One is short-term regulation, which fat ugly girls can come about through events such as substrate availability, allosteric effectors and/or enzyme modification. The other mechanism, long-term regulation, is achieved by alteration fat ugly girls of the rate of enzyme synthesis and turn-over. ACC is the rate-limiting (committed) step in fatty acid synthesis. This enzyme is activated by citrate and inhibited by palmitoyl-CoA and other long-chain fatty acyl-CoAs. ACC activity can also be affected by phosphorylation. For instance, glucagon-stimulated increases in PKA activity result in the phosphorylation fat ugly girls of certain serine residues in ACC leading to decreased activity of the enzyme. By contrast, insulin leads to PKA-independent phosphorylation of ACC at sites distinct from glucagon, which bring about increased ACC activity.
|
