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Interleukin-6 (IL-6) is produced and released into the systemic circulation from subcutaneous adipose lyrics to bounce by fatty koo tissue as well as from cells of the immune system [74](Table 2). The levels correlate with BMI lyrics to bounce by fatty koo and percent body fat. A recent theory is that increased IL-6 may be the link between obesity and insulin resistance [75]. Adipose tissue secretes IL-6 whose levels and those of C-reactive protein also correlate with obesity and insulin resistance. There is strong evidence supporting the central role of IL-6 in the inflammatory response. IL-6 is a 26 kDa cytokine, produced by many different cells in the body, lyrics to bounce by fatty koo including lymphocytes, monocytes, fibroblasts and endothelial cells. Various cytokines are involved in acute phase protein synthesis, including TNF and IL-1ß.
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