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| nutrition/agriculturenews, heart disease, artery damaging lipoprotein, information, crohns disease, organic, unsaturated fatty acids / health aspects, fatty acid, dinner recipe, homeopathy, fish oils, mirkin, asthma/respiratorynews, cell based assay, health supplements, drying oil, health & fitness / nutrition, chronic, omega minus three fatty acids , fat, high blood pressure, trans, | PAF is synthesized in response to the formation of antigen-IgE complexes on the surfaces of basophils, gum disease neutrophils, eosinophils, macrophages and monocytes. The synthesis and release of PAF from cells leads to platelet aggregation and gum disease the release of serotonin from platelets. PAF also produces responses in liver, heart, smooth muscle, and uterine and lung tissues. structure of PAF back to the top Basic Structure of Sphingolipids Sphingolipids are composed of a backbone of sphingosine which is derived itself from glycerol. Sphingosine is N-acetylated by a variety of fatty acids generating a family of molecules referred to as ceramides. Sphingolipids predominate in the myelin sheath of nerve fibers. |
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| Basic composition of a phospholipid. X can be a number of different substituents. back to information the top Basic Structure of information Plasmalogens Plasmalogens are complex membrane lipids that resemble phospholipids, principally phosphatidylcholine. The major difference is that the fatty acid at C-1 (sn1) of glycerol contains either an O-alkyl (-O-CH2-) or O-alkenyl ether (-O-CH=CH-) species. A basic O-alkenyl ether species is shown in the Figure below. information basic composition of O-alkenyl plasmalogens One of the most potent alkyl ether plasmalogens is platelet activating factor (PAF: 1-O-1'-enyl-2-acetyl-sn-glycero-3-phosphocholine) which is a choline plasmalogen in which the C-2 (sn2) position of glycerol is esterified with an acetyl group insted of a long chain fatty acid. PAF functions as a mediator of hypersensitivity, acute inflammatory reactions and anaphylactic shock. |
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