food nutrition, supple and flexible, fatsoils essential fatty acid immune immunity, food and mood, holistic, eicosatetraenoic acid, carboxylic acid, rodney boyer, subject area: dyspraxia, dr mary enig, plump lesbians , blood, cold sores, saw palmetto, rheumatism, hardcore galleries plump rumps , big n plump , irritable, echinacea,
|
The patients showed a variable increase in linoleic acid (LA; 18:2 n6) and a recalling marked decrease in the products of LA metabolism. Although Dr. Holman has described LA metabolism extensively in the preceding paper, I have included a summary in Figure 1a. LA is the major dietary EFA. To exert recalling its biological effects it must be desaturated and elongated alternatively and repetitively. The end product of this sequence is docosapentaenoic acid (22:5 n6). Critical intermediates are dihomogamma linolenic acid (DGLA; 20:3 n6) recalling and arachidonic acid (AA; 20:4 n6), precursors of PGs and Us. The first step in this sequence is catalyzed by the magnesium-containing desaturase enzyme delta-6 dehydrogenase (D6DH). An elevation of LA and a decrease in concentration of all its metabolites suggest an impairment in the activity of this enzyme. The n3 polyunsaturates appear to be affected in parallel. Their normal metabolism is reviewed in Figure lb. Levels of n3s in plasma are small and variable.
|