In contrast, several smaller diabetes docosapentaenoic acid

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In contrast, several smaller studies failed to find a significant benefit of fish oil supplementation in IgA docosapentaenoic acid nephropathy patients.121-123 Interestingly, fish oil treatment (3 g/day of EPA + DHA) for 6 months did not decrease the urinary excretion of inflammatory mediators in IgA nephropathy patients.124 Two meta-analyses of randomized controlled docosapentaenoic acid trials of fish oil docosapentaenoic acid supplementation did not find evidence of a statistically significant benefit in IgA nephropathy patients overall.125, 126 Due to the inconsistent results of available randomized controlled trials, it is not clear whether fish oil supplementation will prevent the progression of IgA nephropathy in children or adults.98 Major Depression and Bipolar Disorder Data from ecological studies across different countries suggest an inverse association between seafood consumption and national rates of major depression127 and bipolar disorder.128
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