average). The first approach essential fatty acids. selenium
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average). The first approach uses only the effect of trans fats on blood lipids, and ignores the associations observed in epidemiological studies. As shown above (Figure 1), replacing 2% energy from cis unsaturated fat with an isocaloric amount of trans fat causes a 0.13 increase in selenium the LDL/HDL cholesterol ratio (we used this because the effect of trans selenium on the total/HDL cholesterol ratio that we used in the past was not provided in one of the new studies). selenium Since a change in one unit in the total/HDL cholesterol ratio has been associated with a 53% change in the CHD risk,47 we estimated a relative risk of 1.07 (1 + 0.53 x 0.13) for a 2% increase in trans fat (the use of LDL/HDL ratio instead of total/HDL cholesterol ratio has trivial effects), corresponding to an attributable risk of 6.5%
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